Medial-prefrontal Enhancement During Schizophrenia Systems Imaging

Summary

This randomized controlled trial in healthy controls (HC) and patients with schizophrenia (SZ) aims to examine 1) the underlying cognitive and neural cause of self-agency deficits in SZ; 2) the responsiveness to a novel navigated repetitive transcranial magnetic stimulation (nrTMS) target in the medial/superior prefrontal cortex (mPFC); and 3) how modulation of mPFC activity impacts the larger self-agency network to mediate changes in self-agency judgments. Our overall hypothesis is that increas

Eligibility

Inclusion Criteria: All Subjects: * Good general physical health * English is first language * No neurological disorder * Meets MRI criteria * No current alcohol or substance use disorder Schizophrenia participants: * Schizophrenia diagnosis of any illness duration, * Clinical stability, defined

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