fNIRS-BCI Neurofeedback in Stroke Rehabilitation

Summary

Objectives: 1) To compare the effects of closed-loop brain-computer interface (BCI) driven observational imitation training versus sham BCI open-loop observational imitation training on improving upper limb motor functions in patients with stroke; 2) To investigate whether stroke patients receiving closed-loop training exhibit higher activation levels in the mirror neurons, measured by event-related desynchronization (ERD), compared to those receiving open-loop training. Hypothesis to be tested

Eligibility

Inclusion Criteria 1. unilateral upper extremity motor deficits caused by ischemic stroke, confirmed by medical documents such as discharge summary and/or neuroimaging examinations. 2. chronic phase of stroke, i.e., time after stroke onset more than six months. 3. aged between 18 and 75 years old.

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