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Parkinson's Neurostimulation trials

Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease

RecruitingNCT06399731Phase: NAStarted 2024-05-31

Summary

This cross-over pilot study aims to study the acceptability of two methods of non-invasive brain stimulation for the treatment of Parkinson's disease mild cognitive impairment (PD-MCI) - repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) targeted at the left dorsolateral prefrontal cortex (DLPFC). Twenty participants will undergo both interventions in a cross-over design. They sequentially undergo four consecutive phases (4 weeks each), 1) no-i

Eligibility

Sex
ALL
Min Age
None
Max Age
None

Inclusion Criteria: * Clinical diagnosis of Parkinson's disease, diagnosed by a neurologist; * Mild to moderate disease stage (Hoehn \& Yahr disease stage \< 4); * Movement Disorders Society level I criteria for PD-MCI (Litvan et al., 2012): * Montreal Cognitive Assessment score range \[21-25\]

Locations

Amsterdam UMC
Amsterdam, North Holland, Netherlands

Interested in participating? View the full study details on ClinicalTrials.gov:

View on ClinicalTrials.gov →